Assay Development

Custom analytical methods are often required when commercially available assays cannot answer specific scientific questions or meet the performance requirements of a project.

Attoquant Diagnostics develops and validates customized LC-MS/MS assays for peptides, steroids, investigational medicinal products (IMPs), metabolites, biomarkers, and other small molecules. Every method is tailored to the analytical objectives, biological matrix, and study design.

Our assays are developed using high-sensitivity LC-MS/MS and stable isotope-labeled internal standards to ensure maximum specificity, sensitivity, and reproducibility from development through routine application.

Why Custom Assay Development Matters

Novel drug candidates, emerging biomarkers, and specialized research questions often require analytical methods that are not commercially available.

Reliable assay development is essential to ensure accurate quantification, robust validation, and reproducible data throughout preclinical and clinical research.

Our Approach

We work closely with our partners to design fit-for-purpose LC-MS/MS assays tailored to their scientific objectives.

Our development process includes assay design, optimization, validation, and implementation, with particular attention to sample preparation, analytical performance, and long-term robustness.

Whether supporting exploratory research or regulated studies, we deliver analytical methods that generate reliable and publication-ready data.

Our Services

Applications

Our customized LC-MS/MS assays support a broad range of research and drug development applications, including:

  • ADME studies
  • Pharmacokinetic (PK) studies
  • Pharmacodynamic (PD) studies
  • Biomarker analysis
  • Translational research
  • Clinical studies

Methods can be developed for peptides, steroids, biomarkers, investigational medicinal products (IMPs), metabolites, and other small molecules across various biological matrices.

Tailored Development & Scientific Support

Every research project has unique analytical requirements.

Whether you need a completely new assay, adaptation of an existing method, support for challenging analytes, or guidance on study design and sample handling, our scientists work with you to develop the optimal analytical solution.

Contact us today to discuss your project.

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Attoquant Diagnostics GmbH
Brehmstraße 14A
1110 Vienna
Austria

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